After a convincing win over New Zealand in the Autumn internationals, France (11/8 Six Nations outright) are understandably the favourites going into the 2022 Six Nations Championship.
However, the likes of Ireland, England, Wales and Scotland will harbour their own ambitions to finish at the top of the pile in a championship that looks like it could go right down to the wire.
England (11/4) head coach Eddie Jones has been plagued by injuries going into their opening game of the tournament against Scotland on Saturday.
The likes of Owen Farrell, Jonny May and Anthony Watson are all out for the tournament, while Courtney Lawes and Jonny Hill are the latest players to be ruled out of the trip to Murrayfield.
It looks set to be a new-look England to take on what appears to be a settled Scotland (10/1 outright) side that managed wins in both London and Paris last season.
The result in Edinburgh at the weekend will have a big say on how these two rivals fare in the competition this year.
Six Nations Betting Odds
With the Irish Provinces shining both in the United Rugby Championship and in Europe, much is expected of Ireland (11/4) going into the Six Nations.
A blend of experience and youth, with a game based on structure and power, means Ireland are also expected to be serious contenders.
Ireland open the tournament at home to a Wales (12/1) side which seems to be going through a transitional phase, despite entering the competition as defending champions.
Injuries have also played their part for Wayne Pivac’s side, with skipper Alun Wyn Jones set to miss out on most, if not all, of the championship.
France should have little trouble breezing past Italy in their opening game in Paris on Sunday.
Italy (500/1) look set for another tough tournament after failing to register a point in the competition last year.
All eyes are on France (10/3 Grand Slam) and whether they can handle that favourite’s tag, especially leading into a home World Cup for Les Bleus next year.
Rugby Union Betting Odds